Publications
13. Liu, H.; Zeng, T.; He, C.; Rawal, V.H.;听Zhou, H*.; Dickinson, B.C*. (2022) Development of Mild Chemical Catalysis Conditions for m1A-to-m6A Rearrangement on RNA.听ACS Chemical Biology听Article ASAP.
DOI: 10.1021/acschembio.2c00178
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12. Rangadurai, A.;听Shi, H.;听Xu, Y.;听Liu, B.; Assi, H. A.;听Boom, J.D.;听Zhou, H.;听 Kimsey,听I. J.;听Al-Hashimi, H.M. (2022) Measuring thermodynamic preferences to form non-native conformations in nucleic acids using melting experiments reveals a rich sequence-specific DNA conformational landscape.听BioRxiv.
11. Shafik, A.M.,听Zhou H., Lim J., Dickinson, B.C., Jin P. (2021)听Dysregulated mitochondrial and cytosolic tRNA m1A methylation in Alzheimer鈥檚 disease.听Hum. Mol. Genet.听ddab357.
10.听Zhou, H.; Rauch, S.; Dai, Q.; Cui, X.; Zhang, Z.; Nachtergaele, S.; Sepich, C.; He, C.; Dickinson, B.C. (2019) Evolution of A Reverse Transcriptase to Map N1-Methyladenosine in Human mRNA.听Nature Methods. 16, 1281-1288.
9. Rauch, S.; He E.; Scienc M.;听Zhou, H.; Zhang, Z.; Dickinson, B.C. (2019) Programmable RNA-Guided RNA Effector Proteins Built from Human Parts.听Cell. 178, 8-9.
8.听Zhou, H.; Sathyamoorthy, B.; Stelling, A.; Xu, Y.; Xue, Y.;听 Pigli, Y. Z.; Case, D.; Rice, P. A.; Al-Hashimi, H. M. (2019) Resolving crystallographic ambiguity in Watson-Crick versus Hoogsteen base-pairing in a DNA-protein complex using NMR and site-specifically 13C/15N labeled DNA.听Biochemistry, 58, 1963-1974.
7. Rangadurai, A.;听Zhou, H.; Merriman, D.; Meiser, N.; Liu, B.; Shi, H.; Szymanski, E.; Al-Hashimi, H.M. (2018) Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA?听Nucleic Acids Res., 46, 11099-11114.
6. Sathyamoorthy, B.; Shi, H.;听Zhou, H.; Xue, Y; Rangadurai A.; Merriman D. K.; Al-Hashimi, H. M. (2017) Insights into Watson-Crick/Hoogsteen Breathing Dynamics and Damage Repair from the Solution Structure and Dynamic Ensemble of DNA Duplexes containing m1A.听Nucleic Acids Res., 45, 5586-5601.
5. Stelling, A.; Xu, Y.;听Zhou, H.; Choi, S.; Clay, M.; Merriman, D.; Al-Hashimi, H. M. (2017) Robust IR Based Detection of Stable and Fractionally Populated G鈥怌+ and A鈥怲 Hoogsteen Base Pairs in Duplex DNA.听FEBS Letters, 591, 1770-1784.
4.听Zhou, H.; Kimsey, I. J.; Nikolova, E. N.; Sathyamoorthy, B.;Grazioli, G.; McSally, J.;Bai, T.; Wunderlich, C. H.; Kreutz,C.; Andricioaei, I.;Al-Hashimi, H. M. (2016) m1A and m1G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs.听Nat. Struct. Mol. Biol., 23, 803-810.
3.听Zhou, H.; Hintze B.J.; Kimsey, I. J.; Sathyamoorthy, B.; Yang S.; Richardson, J.S.; Al-Hashimi, H. M. (2015) New insights into Hoogsteen base pairs in DNA duplexes from a structure-based survey.听Nucleic Acids Res.,听43, 3420-3433.
2. Nikolova, E.N.;听Zhou, H.; Gottardo F.L.; Alvey, H. S.; Kimsey, I. J.; Al-Hashimi, H. M. (2013) A Historical Account of Hoogsteen Base-Pairs in Duplex DNA.听Biopolymers,99, 955-968.
1. Goh, G.B.; Hulbert B.S.;听Zhou, H.; Brooks. C.L. 3rd. (2014) Constant pH molecular dynamics of proteins in explicit solvent with proton tautomerism.听Proteins, 82, 1319-1331.